Yrr Asbjørg Mørch
Yrr Asbjørg Mørch
Publikasjoner og ansvarsområder
Structural Variants of poly(alkylcyanoacrylate) Nanoparticles Differentially Affect LC3 and Autophagic Cargo Degradation
Nanoparticle drug carriers trigger a variety of cellular stress responses, including ER stress and antioxidant responses, but may also affect the intracellular degradative pathway autophagy. This can impose profound effects on drug delivery, cellular treatment responses, and nanoparticle cytotoxicit...
Therapeutic effect of cabazitaxel and blood-brain barrier opening in a patient-derived glioblastoma model
Effect of ultrasound on the vasculature and extravasation of nanoscale particles imaged in real time
Effect of Ultrasound on the Vasculature and Extravasation of Nanoscale Particles Imaged in Real Time
Ultrasound and microbubbles have been found to improve the delivery of drugs and nanoparticles to tumor tissue. To obtain new knowledge on the influence of vascular parameters on extravasation and to elucidate the effect of acoustic pressure on extravasation and penetration of nanoscale particles in...
Small variations in nanoparticle structure dictate differential cellular stress responses and mode of cell death
Blood brain barrier opening and Therapeutic Effect of Free and Nanoencapsulated Cabazitaxel in an Invasive Patient-Derived Glioblastoma Model
From Drug Discovery to Preclinical Studies: SINTEFs Nanoparticle-Based Technologies for Cancer Treatment
The Effect of Sonication on Extravasation and Distribution of Nanoparticles and Dextrans in Tumor Tissue Imaged by Multiphoton Microscopy
Ultrasound (US)and systemic administration of microbubbles (MBs)have been shown to improve the delivery of drugs and nanoparticles (NPs)to tumor tissue. A better understanding of the mechanisms is crucial for effective delivery of NPs and drugs. To elucidate the kinetics of extravasation events, and...