Lytic polysaccharide monooxygenases (LPMOs) catalyze oxidative cleavage of recalcitrant polysaccharides such as cellulose and chitin and play an important role in the enzymatic degradation of biomass. While it is clear that these monocopper enzymes have extended substrate-binding surfaces for intera...

Bioactive chemicals produced by microorganisms isolated from nature have been the source of most antibiotics in medical use today. However, many antibiotics are currently losing their potency due to rapidly spreading antibiotic resistance among pathogenic bacteria. Coincidently, very few new antibio...