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Increased reactivity and in vitro cell response of titanium based implant surfaces after anodic oxidation

Increased reactivity and in vitro cell response of titanium based implant surfaces after anodic oxidation

Kategori
Vitenskapelig artikkel
Sammendrag
In the quest for improved bone growth and attachment around dental implants, chemical surface modifications are one possibility for future developments. The biological properties of titanium based materials can be further enhanced with methods like anodic polarization to produce an active rather than a passive titanium oxide surface. Here we investigate the formation of hydroxide groups on sand blasted and acid etched titanium and titanium–zirconium alloy surfaces after anodic polarization in an alkaline solution. X-ray photoelectron spectroscopy shows that the activated surfaces had increased reactivity. Furthermore the activated surfaces show up to threefold increase in OH− concentration in comparison to the original surface. The surface parameters Sa, Sku, Sdr and Ssk were more closely correlated to time and current density for titanium than for titanium–zirconium. Studies with MC3T3-E1 osteoblastic cells showed that OH− activated surfaces increased mRNA levels of osteocalcin and collagen-I.
Oppdragsgiver
  • Research Council of Norway (RCN) / 203034
  • Research Council of Norway (RCN) / 203036
Språk
Engelsk
Forfatter(e)
  • Martin Sebastian Walter
  • Matthias Johannes Frank
  • Martin Fleissner Sunding
  • Manuel Gomez-Florit
  • Marta Monjo Cabrer
  • Miroslaw M. Bucko
  • Elzbieta Pamula
  • Ståle Petter Lyngstadaas
  • Håvard Jostein Haugen
Institusjon(er)
  • Universitetet i Oslo
  • Technische Universität München
  • SINTEF Industri / Bærekraftig energiteknologi
  • Universitat de les Illes Balears
  • Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie
År
Publisert i
Journal of materials science. Materials in medicine
ISSN
0957-4530
Årgang
24
Hefte nr.
12
Side(r)
2761 - 2773