Til hovedinnhold

Separation and Concentration without Clogging Using a High-Throughput Tunable Filter

Separation and Concentration without Clogging Using a High-Throughput Tunable Filter

Kategori
Tidsskriftspublikasjon
Sammendrag
We present a detailed experimental study of a hydrodynamic filtration microchip and show how chip performance can be tuned and clogging avoided by adjusting the flow rates. We demonstrate concentration and separation of microspheres at throughputs as high as 29  ml/min and with 96% pureness. Results of streakline visualizations show that the thickness of a tunable filtration layer dictates the cutoff size and that two different concentration mechanisms exist. Particles larger than pores are concentrated by low-velocity rolling over the filtration pillars, while particles smaller than pores are concentrated by lateral drift across the filtration layer. Results of microscopic particle image velocimetry and particle-tracking velocimetry show that the degree of lateral migration can be quantified by the slip velocity between the particle and the surrounding fluid. Finally, by utilizing differences in inertia and separation mode, we demonstrate size-based separation of particles in a mixture
Oppdragsgiver
  • Norges forskningsråd / 232148
Språk
Engelsk
Forfatter(e)
Institusjon(er)
  • Universitetet i Oslo
  • Trilobite Microsystems AS
  • SINTEF Digital / Microsystems and Nanotechnology
År
2018
Publisert i
Physical Review Applied
ISSN
2331-7019
Forlag
American Physical Society
Årgang
9
Hefte nr.
5