Til hovedinnhold

The use of flow chemistry for two-phase dibromocyclopropanation of alkenes

The use of flow chemistry for two-phase dibromocyclopropanation of alkenes

Kategori
Tidsskriftspublikasjon
Sammendrag
Conventional batch dibromocyclopropanations by reaction of bromoform and alkenes under phase-transfer conditions require strong base (50% NaOH (aq)), vigorous stirring, and often long reaction times. Using flow chemistry in a microreactor, the reactions were found to be smooth, rapid, and high-yielding under ambient conditions when 40% (w/w) NaOH was used as the base. The reaction has been tested with a representative selection of alkenes, displaying a variety of structural features.
Språk
Engelsk
Forfatter(e)
Institusjon(er)
  • Norges miljø- og biovitenskapelige universitet
  • SINTEF Industri / Prosessteknologi
År
2015
Publisert i
Journal of Flow Chemistry
ISSN
2062-249X
Forlag
Ungarn, Akadémiai Kiadó
Årgang
5
Hefte nr.
2
Side(r)
69 - 73