We formulate and encapsulate drugs for efficient delivery and optimal effect, offer advanced characterization of active substances and investigate their effect on the body.
We apply nanomedicine in:
| Nanoformulation technologies | Material science | Physico-chemical characterization | In vitro assays | In vivo studies |
Many drugs are either unstable or difficult to administrate and deliver. We provide tailored nanoformulation solutions for a wide range of small molecular drugs and biomolecules.
We use emulsion-based, nanoprecipitation, self-assembly and layer-by-layer methods to produce:
SINTEF provides expertise within material chemistry, ranging from surface modification to chemical synthesis.
SINTEF has state-of-the art infrastructure for performing standardized and custom characterization of nanomaterials. We offer one of Europe's most advanced mass spectrometry and analysis facility.
Size, size distribution, concentration and zetapotential
Our high-throughput screening facility includes four pipetting robots, allowing efficient and accurate screening of nanomedicine safety and efficacy.
Robotic screening for in vitro efficacy and toxicity in various cells (e.g. cancer cells, normal cells, bacteria)
SINTEF offers a portfolio of preclinical disease models in rodents. The effect, distibution and pharmacokinetics of drugs and nanomedicines is evaluated using multiple imaging- and analytical methods.
