SINTEF Industry Biotechnology and Nanomedicine
RESEARCH, TECHNOLOGY AND INNOVATION
Biotechnology and nanomedicine are key enabling technologies for various sectors of society and multiple industries. The technology is used in development of pharmaceuticals, vaccines, biomaterials, enzymes, food, feed, chemicals and energy. SINTEF Industry has a strong operation in the fields of microbial molecular biology, bioprocess- and medical technology, biopolymers/polymers, biopharmaceuticals and nanomedicine, and is operating a state-of-the-art research infrastructure including advanced mass spectrometry.
High throughput screening facility, Trondheim
The robotic screening facility at SINTEF are optimized for high throughput analytical and cultivation work and enables us to process of thousands of samples or cultures per day.
Molecular biology laboratory
We have state of the art equipment for molecular biology, including an Illumina MiSeq sequencer, droplet digital PCR (ddPCR), Agilent Bioanalyzer, CHEF Mapper XA pulse field gel electrophoresis system and a Bluepippin cassette-based gel electrophoresis system for DNA and protein separation, in addition to ÄKTA FPLC equipment for protein purification. Our co-workers have several years of experience and master most topics and protocols related to genetic modification of bacteria.
Fermentation laboratory at SINTEF
SINTEF has a nationally leading research laboratory for development of microbial and cell based production processes. The laboratory has robotic equipment for miniaturized cultivation, large capacity incubators for shake flasks, laboratory fermentors (1-3 L) equipped for extensive process control and monitoring, and a pilot plant with two fermenters (50 and 300 L) for scale-up studies and small productions.
Mucoprotect – A novel generic system for targeted delivery of oral vaccines
Vaccines are by far the most important tool in preventing disease in Norwegian aquaculture. Without the systematic use of efficient vaccines industrialisied fish farming would be an impossibility. Despite this, 53 million salmon were lost in Norway in 2017 due to illness and injury, also related to salmon lice treatment. In the project we will develop novel, clever vaccines based on nanoparticles, tailored for oral vaccination.
CARBIOMEMBEX - Novel biocatalytic membrane technology for the efficient removal of CO2 in Recirculating Aquaculture Systems
CO2 removal from process water is an essential component of land-based aquaculture. CARBIOMEMBEX aims at developing novel technology for CO2 separation in aquaculture by combining state-of-the-art membrane technology and biocatalysis into innovative enzyme-membrane contactor systems for efficient CO2 removal from water.
Experiments show that an “unknown” enzyme fights inflammation
An enzyme that normally repairs damaged DNA may be the key to a new treatment for inflammatory diseases.
Hoping to treat osteoarthritis using artificial cartilage tissue
A Norwegian-Swiss research team has succeeded in growing cartilage tissue cells using algae. Moreover, the new cells can reduce joint inflammation. This news gives hope for people suffering from arthrosis, also known as osteoarthritis.
New allergy test promises safer antibiotic use
Allergies to antibiotics are the commonest form of medication allergies and, in the worst cases, can result in anaphylaxis and death. SINTEF is participating in the development of a new allergy test that will make it easier to provide patients with safe and correct treatments.