To main content

Increased reactivity and in vitro cell response of titanium based implant surfaces after anodic oxidation

Abstract

In the quest for improved bone growth and attachment around dental implants, chemical surface modifications are one possibility for future developments. The biological properties of titanium based materials can be further enhanced with methods like anodic polarization to produce an active rather than a passive titanium oxide surface. Here we investigate the formation of hydroxide groups on sand blasted and acid etched titanium and titanium–zirconium alloy surfaces after anodic polarization in an alkaline solution. X-ray photoelectron spectroscopy shows that the activated surfaces had increased reactivity. Furthermore the activated surfaces show up to threefold increase in OH− concentration in comparison to the original surface. The surface parameters Sa, Sku, Sdr and Ssk were more closely correlated to time and current density for titanium than for titanium–zirconium. Studies with MC3T3-E1 osteoblastic cells showed that OH− activated surfaces increased mRNA levels of osteocalcin and collagen-I.

Category

Academic article

Language

English

Author(s)

  • Martin Sebastian Walter
  • Matthias Johannes Frank
  • Martin Fleissner Sunding
  • Manuel Gomez-Florit
  • Marta Monjo
  • Miroslaw M. Bucko
  • Elzbieta Pamula
  • Ståle Petter Lyngstadaas
  • Håvard Jostein Haugen

Affiliation

  • University of Oslo
  • Technical University of Munich
  • SINTEF Industry / Sustainable Energy Technology
  • University of the Balearic Islands
  • AGH University of Science and Technology

Year

2013

Published in

Journal of materials science. Materials in medicine

ISSN

0957-4530

Volume

24

Issue

12

Page(s)

2761 - 2773

View this publication at Cristin