This paper describes a set of guidelines defined for marine autonomous operations where many actors, devices and sensors are interacting. The UI should manage and present in a user-friendly manner a large amount of data, ensuring situation awareness for the operator/user. The design guidelines of the user interface consist of both a work process part and a content part, also called user experience design (UX). The work process consists of four sections: manage, plan, operate and evaluate, while the content part focuses on how to show the information. Both parts will be detailed and discussed and can be taken as a reference for designing user interfaces in particular for marine autonomous operations.