Hydrodynamic simulations of a pseudo-2D bubbling fluidized bed were carried out and compared to experiments conducted over a wide range of flow conditions. The primary purpose of this study was to assess the generality of the standard 2D Two Fluid Model (TFM) closed by the Kinetic Theory of Granular Flows (KTGF) which is regularly used in the literature to simulate bubbling fluidized beds. Comparisons of the bed expansion ratio over wide ranges of fluidization velocity, bed loading and particle size showed systematic differences between simulations and experiments, indicating that the generality of this modelling approach is questionable. More detailed flow velocity measurements collected via Particle Image Velocimetry (PIV) showed that the model greatly over-predicts flow velocities in the bed. Subsequent 3D simulations showed this over-prediction to be the result of 2D simulations neglecting the wall friction at the front and back walls of the pseudo-2D bed.