Immuno – New Methods for cancer immunotherapy
The main goal of this project is to develop SINTEF’s competence within biotechnology and drug discovery/development to also include immunotherapies.
Mucoprotect – A novel generic system for targeted delivery of oral vaccines
Vaccines are by far the most important tool in preventing disease in Norwegian aquaculture. Without the systematic use of efficient vaccines industrialisied fish farming would be an impossibility. Despite this, 53 million salmon were lost in Norway in 2017 due to illness and injury, also related to salmon lice treatment. In the project we will develop novel, clever vaccines based on nanoparticles, tailored for oral vaccination.
CARBIOMEMBEX - Novel biocatalytic membrane technology for the efficient removal of CO2 in Recirculating Aquaculture Systems
CO2 removal from process water is an essential component of land-based aquaculture. CARBIOMEMBEX aims at developing novel technology for CO2 separation in aquaculture by combining state-of-the-art membrane technology and biocatalysis into innovative enzyme-membrane contactor systems for efficient CO2 removal from water.
REFINE - Regulatory Science Framework for Nano(bio)material-based Medical Products and Devices
REFINE will pioneer a Regulatory Science Framework (RSF) for the risk-benefit assessment of NBM-based medicinal products and medical devices.
BarkCure - Condensed tannins from Norwegian pine and spruce bark - antiparasitic effects and potential commercial exploitation
Condensed tannins (CT) are regarded as anti-nutrients as they may reduce feed intake, nutrient digestion and production in livestock. However, the inclusion of small amounts of CT in the diet of ruminants may decrease problems with gastrointestinal parasites. Tannin containing forages are not well adapted to Norwegian cultivation conditions, but Norway has a strong forest industry and bark harvested from conifer species may have high content of CT.
AurOmega - Microbial production of omega-3 fatty acids - a model based approach
The systems biology approach in AurOmega will provide an enhanced understanding of what limits the DHA synthesis in thraustochytrids and how it can be improved. An iterative approach applying high integration of experimental disciplines, with extensive omics analyses and mathematical modelling will be used.
DAFIA - Biomacromolecules from municipal solid bio-waste fractions and fish waste for high added value applications
The main objective of DAFIA is to exploit municipal solid wastes (MSW) and marine rest raw materials (MRRM) as feedstocks for higher value products. Municipal solids wastes represents more than 500 kg/capita (EU-27 average) and 300 million tonnes overall every year in the EU-32. Currently, approximately 50% of this volume is landfilled, while the rest is incinerated for energy production.
B-SMART - Brain-Specific, Modular and Active RNA Therapeutics
An Innovative nanotechnological RNA delivery systems targeting the direct cause of Alzheimer‘s disease instead of its symptoms. The overall objective of B-SMART is to design modular nanoparticles, to manufacture them via a quality-by-design protocol, and to achieve delivery of therapeutic RNAs to the brain and treat neurodegenerative diseases.