Publications and responsibilities
Blood brain barrier opening and Therapeutic Effect of Free and Nanoencapsulated Cabazitaxel in an Invasive Patient-Derived Glioblastoma Model
From Drug Discovery to Preclinical Studies: SINTEFs Nanoparticle-Based Technologies for Cancer Treatment
Effect of ultrasound on the vasculature and extravasation of nanoscale particles imaged in real time
3DLife: Validating new high-throughput methods for 3D cell culture screening
The Effect of Sonication on Extravasation and Distribution of Nanoparticles and Dextrans in Tumor Tissue Imaged by Multiphoton Microscopy
Ultrasound (US)and systemic administration of microbubbles (MBs)have been shown to improve the delivery of drugs and nanoparticles (NPs)to tumor tissue. A better understanding of the mechanisms is crucial for effective delivery of NPs and drugs. To elucidate the kinetics of extravasation events, and...
Sonoporation enhances delivery of nanomedicine for improved cancer treatment
Extravasation and distribution of nanoparticles and 2MDa dextran in tumor imaged by multiphoton microscopy during ultrasound sonication.
Ultrasound-mediated delivery and distribution of polymeric nanoparticles in the normal brain parenchyma of a metastatic brain tumour model
The treatment of brain diseases is hindered by the blood-brain barrier (BBB) preventing most drugs from entering the brain. Focused ultrasound (FUS) with microbubbles can open the BBB safely and reversibly. Systemic drug injection might induce toxicity, but encapsulation into nanoparticles reduces a...