SINTEF Industry Biotechnology and Nanomedicine
RESEARCH, TECHNOLOGY AND INNOVATION
Biotechnology and nanomedicine are key enabling technologies for various sectors of society and multiple industries. The technology is used in development of pharmaceuticals, vaccines, biomaterials, enzymes, food, feed, chemicals and energy. SINTEF Industry has a strong operation in the fields of microbial molecular biology, bioprocess- and medical technology, biopolymers/polymers, biopharmaceuticals and nanomedicine, and is operating a state-of-the-art research infrastructure including advanced mass spectrometry.
High throughput screening facility, Trondheim
The robotic screening facility at SINTEF are optimized for high throughput analytical and cultivation work and enables us to process of thousands of samples or cultures per day.
Molecular biology laboratory
We have state of the art equipment for molecular biology, including an Illumina MiSeq sequencer, droplet digital PCR (ddPCR), Agilent Bioanalyzer, CHEF Mapper XA pulse field gel electrophoresis system and a Bluepippin cassette-based gel electrophoresis system for DNA and protein separation, in addition to ÄKTA FPLC equipment for protein purification. Our co-workers have several years of experience and master most topics and protocols related to genetic modification of bacteria.
Fermentation laboratory at SINTEF
SINTEF has a nationally leading research laboratory for development of microbial and cell based production processes. The laboratory has robotic equipment for miniaturized cultivation, large capacity incubators for shake flasks, laboratory fermentors (1-3 L) equipped for extensive process control and monitoring, and a pilot plant with two fermenters (50 and 300 L) for scale-up studies and small productions.
Mucoprotect – A novel generic system for targeted delivery of oral vaccines
Vaccines are by far the most important tool in preventing disease in Norwegian aquaculture. Without the systematic use of efficient vaccines industrialisied fish farming would be an impossibility. Despite this, 53 million salmon were lost in Norway in 2017 due to illness and injury, also related to salmon lice treatment. In the project we will develop novel, clever vaccines based on nanoparticles, tailored for oral vaccination.
SIP GUT: Development of tools for gut microbiota research
The gut microbiota are the microorganisms that live in the gastrointestinal tract. They play a fundamental role in health and disease of the host. Detailed understanding of gut microbiota–host interactions is therefore of great importance as this may be used to find new treatments to various diseases and increase the well-being of humans and animals.
TrippelTarg - Triple Targeting of Biodegradable Nanoparticles for Treatment of Cancer
SINTEF want to further develop a targeted treatment strategy that has shown promising effects in animals with patient-derived tumors. The strategy is based on the use of nanoparticles developed by SINTEF containing a cytostatic drug.
How safe are the new Covid vaccines?
The new vaccines designed to combat the Covid-19 virus have been developed in record time, causing some people to be sceptical of taking them. Should we be worried about side effects? Norwegian SciTech News has been talking to two research scientists about this issue.
Getting the body to make its own cancer drugs
Imagine that we could instruct our bodies to make the drugs they need themselves. The gene technology that makes this possible is called mRNA therapy, which may become a major tool in the treatment of multiple diseases. Norwegian researchers are currently helping to develop a drug of this kind to treat the most aggressive form of breast cancer.