Lab scale fermentation
Characterization of microorganisms by controlled and reproducible cultivation in liquid media is a fundamental tool for in-depth studies of the organism’s physiology and biology.
Our department offers two highly automated laboratory scale fermentation laboratories for efficient strain and process evaluation.
|
Each of the two laboratories consists of 16 vessels with an operating volume of 0.75 to 2 liter, and offers highly controlled and extensively monitored high cell density batch, fed-batch and chemostat cultures. The laboratories are custom-built by our own in-house engineers and biotechnology researchers. This offers an important flexibility as we can customize unique software and hardware solutions for specific and dynamic project requirements.
The laboratory is used for a range of purposes, as for example
-
optimization of industrial strains and microbial processes
-
in-depth basic studies of physiology and biology of microorganisms
-
research-based production of new biological compounds for subsequent structure identification and/or characterization |
 |
Our fermentation laboratory is being used in a number of collaboration projects with national and international partners within industry and academia. We are open-minded and enthusiastic towards new collaborations with new partners.
Specifications
-
32 Applicon fermentation vessels, 3 liter scale
-
Automatic control and online monitoring of operating conditions such as dissolved oxygen, pH, agitation speed and temperature.
-
Online mass-spectroscopy gas analysis of inlet and exhaust gas.
-
Online mass-spectroscopy-based analysis of alcohol-concentration in fermentation medium.
-
Computer-controlled logging and online visualization of fermentation profile.
-
Customized control-engineering algorithms for user-defined substrate feeding profiles
(feed-rate or set-point).
