Lab scale fermentation
Characterization of microorganisms by controlled and reproducible cultivation in liquid media is a fundamental tool for in-depth studies of the organism’s physiology and biology. Our department offers two highly automated laboratory scale fermentation laboratories for efficient strain and process evaluation.

Each of the two laboratories consists of 16 vessels with an operating volume of 0.75 to 2 liter, and offers highly controlled and extensively monitored high cell density batch, fed-batch and chemostat cultures. The laboratories are custom-built by our own in-house engineers and biotechnology researchers. This offers an important flexibility as we can customize unique software and hardware solutions for specific and dynamic project requirements.

 

The laboratory is used for a range of purposes, as for example

  • optimization of industrial strains and microbial processes
  • in-depth basic studies of  physiology and biology of microorganisms
  • research-based production of new biological compounds for subsequent structure identification and/or characterization
Lab scale fermentation

Our fermentation laboratory is being used in a number of collaboration projects with national and international partners within industry and academia. We are open-minded and enthusiastic towards new collaborations with new partners.

 

Specifications

  • 32 Applicon fermentation vessels, 3 liter scale
  • Automatic control and online monitoring of operating conditions such as dissolved oxygen, pH, agitation speed and temperature.
  • Online mass-spectroscopy gas analysis of inlet and exhaust gas.
  • Online mass-spectroscopy-based analysis of alcohol-concentration in fermentation medium.
  • Computer-controlled logging and online visualization of fermentation profile.
  • Customized control-engineering algorithms for user-defined substrate feeding profiles
    (feed-rate or set-point).

 

 

Lab scale fermentation


Published April 19, 2009

Håvard Sletta
phone +47 930 86 028