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RESEARCH, TECHNOLOGY AND INNOVATION

Biotechnology and nanomedicine are key enabling technologies for various sectors of society and multiple industries. The technology is used in development of pharmaceuticals, vaccines, biomaterials, enzymes, food, feed, chemicals and energy. SINTEF Materials and Chemistry has a strong operation in the fields of microbial molecular biology, bioprocess- and medical technology, biopolymers/polymers, biopharmaceuticals and nanomedicine, and is operating a state-of-the-art research infrastructure including advanced mass spectrometry.

Expertise

Biopharmaceuticals, medical technology and nanomedicine

Discovery, characterisation and production of biopharmaceuticals have been an important research area at SINTEF for more than 25 years. Main focus has been development of microbial production processes. We have established numerous methods, technologies, assays and laboratories to support this activity. Medical technology and Nanomedicine is rapidly growing research areas in SINTEF, where we focus on development of nanoparticles tailored for drug delivery, biosensors, and new solutions for therapy and diagnostics.

Research Manager
982 43 914
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Environmental Biotechnology and Microbiology

Microbial bioprocesses is an important research area at SINTEF Materials and Chemistry. Department of Biotechnology and Nanomedicine has for the last ten years worked with microbial processes related to environmental technology. Examples are conversion of various types of feedstock to biofuel and platform chemicals, expertise within degradation of crude oil and other unwanted and recalcitrant chemicals in nature and bioreactors, and microfouling/biofilm formation on various surfaces from water systems to ship hulls.

Research Scientist
930 85 978
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Food and Feed Microbiology and Biochemistry

Food and feed products may undergo both wanted and unwanted microbial, biochemical and chemical processes and changes during production and storage, e.g. lactic acid fermentation of milk products, microbial and enzymatic ripening of cheese, meat and fish products, and microbial, enzymatic and chemical deterioration of food products during storage. Different strategies may be used to control, promote or prevent these processes. Biotechnological processes may also be used to produce food and feed ingredients, e.g. polyunsaturated fatty acids.

Senior Research Scientist
930 86 027
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Functional metagenomics and enzyme technology

Functional Metagenomics R&D is a relatively new and rapidly growing research area at SINTEF. Building on a long tradition of Marine Bioprospecting at SINTEF and NTNU, it aims at accessing and exploiting the metabolic potential of the entire microbial biodiversity in natural habitats, including the great majority of microorganisms that cannot be readily cultivated under laboratory conditions.

Senior Research Scientist
932 00 776
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High throughput screening

SINTEF has advanced facilities for high throughput screening and is working with lab automation and high throughput screening in a range of projects. The robotic screening facility at SINTEF has state of the art equipment for efficient automation of assays and cultivation in microplate format. Several thousands of samples and cultures are processed per day on a regular basis in the screening facility.

Research Manager
915 44 429
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Mass spectrometry and separation science in Biotechnology

Biological and biotechnological systems are often very complex, containing a large number (hundreds to thousands) of distinct chemical compounds. The use of mass spectrometry (MS) coupled to chromatographic separation (GC, LC, IC, FFF) allows for sensitive and robust quantification (ng/ml and below) of one or several selected compounds. This can be done even when the compound(s) of interest is present at very low concentration and in complex mixtures with closely related molecules. No other analytical technique can provide the same combination of sensitivity, selectivity and specificity for biological systems.

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Systems and synthetic biology

SINTEF Materials and Chemistry, Department of Biotechnology and Nanomedicine has been and currently is coordinating and participating in several transdisciplinary national and international projects aiming at systems scale understanding of microbial cells. The aim is to develop them into efficient microbial cell factories by means of metabolic engineering and applying top-down Synthetic Biology and metabolic engineering approaches.

Senior Research Scientist
932 00 776
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