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• Targeted macromolecule delivery• Photochemically induced drug delivery• Adenovirus and oligonucleotide therapy
• Fate and ecotoxicity of nanomaterials in the environment, including nano-based pharmaceuticals• Methods for detection of nanoparticles in organisms and environmental matrices• Risk assessment of nanomaterials released in the environment• Microbial modification of nanomaterials
• Chitosan-based nanoparticles for non-viral gene delivery is a novel approach to selective transfection in vivo. Nanofabrication and manipulation of chitosan complexes enables tailor-making of non-viral gene delivery vehicles for therapeutic purposes.• Bioresponsive materials as signal transducers for optical detection of specific biological molecules allow biosensing in an environment requiring non-magnetic materials as in e.g. MRI. The materials being developed aim at integration of specific molecules related to the particular diagnostic situation at hand
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Published April 22, 2010